[Antigenic anachronism of influenza viruses A(H2N2) in Leningrad in 1980. II. The laboratory characteristics of influenza A/Leningrad/80 viruses].
Identifieur interne : 002483 ( Main/Exploration ); précédent : 002482; suivant : 002484[Antigenic anachronism of influenza viruses A(H2N2) in Leningrad in 1980. II. The laboratory characteristics of influenza A/Leningrad/80 viruses].
Auteurs : D B Golubev ; S S Galitarov ; Iu M. Poliakov ; O M Litvinova ; A I BannikovSource :
- Zhurnal mikrobiologii, epidemiologii, i immunobiologii [ 0372-9311 ] ; 1984.
Descripteurs français
- KwdFr :
- ARN viral (génétique), Animaux, Antigènes viraux (analyse), DNA-directed RNA polymerases (analyse), Humains, Hybridation d'acides nucléiques, Peptides (analyse), Protéines virales (analyse), Russie, Réactions croisées, Sialidase (antagonistes et inhibiteurs), Sous-type H2N2 du virus de la grippe A, Tests d'inhibition de l'hémagglutination, Virus de la grippe A (enzymologie), Virus de la grippe A (immunologie), Virus de la grippe A (isolement et purification).
- MESH :
- analyse : Antigènes viraux, DNA-directed RNA polymerases, Peptides, Protéines virales.
- antagonistes et inhibiteurs : Sialidase.
- enzymologie : Virus de la grippe A.
- génétique : ARN viral.
- immunologie : Virus de la grippe A.
- isolement et purification : Virus de la grippe A.
- Animaux, Humains, Hybridation d'acides nucléiques, Russie, Réactions croisées, Sous-type H2N2 du virus de la grippe A, Tests d'inhibition de l'hémagglutination.
English descriptors
- KwdEn :
- Animals, Antigens, Viral (analysis), Cross Reactions, DNA-Directed RNA Polymerases (analysis), Hemagglutination Inhibition Tests, Humans, Influenza A Virus, H2N2 Subtype, Influenza A virus (enzymology), Influenza A virus (immunology), Influenza A virus (isolation & purification), Neuraminidase (antagonists & inhibitors), Nucleic Acid Hybridization, Peptides (analysis), RNA, Viral (genetics), Russia, Viral Proteins (analysis).
- MESH :
- chemical , analysis : Antigens, Viral, DNA-Directed RNA Polymerases, Peptides, Viral Proteins.
- chemical , antagonists & inhibitors : Neuraminidase.
- geographic : Russia.
- enzymology : Influenza A virus.
- chemical , genetics : RNA, Viral.
- immunology : Influenza A virus.
- isolation & purification : Influenza A virus.
- Animals, Cross Reactions, Hemagglutination Inhibition Tests, Humans, Influenza A Virus, H2N2 Subtype, Nucleic Acid Hybridization.
Abstract
As indicated by the results of the hemagglutination inhibition (HAI) test, influenza viruses A/Leningrad/80 contain hemagglutinin (HA), similar to that of virus A/Singapore/1/57 (H2N2). Neuraminidase contained in viruses A/Leningrad/80 belongs to serological subtype N2 and is similar to that of virus A/Singapore/1/57 (H2N2). No differences in the polypeptide composition of the virus-induced proteins of viruses A/Leningrad/527/80, A/Leningrad/549/80, A/Leningrad/553/80 and virus A/Singapore/1/57 used as reference have been detected in the study of their electrophoretic mobility in polyacrylamide gel, as well as the mobility of duplexes obtained by the hybridization of the virion and complement RNA of viruses A/Leningrad/553/80 and A/Singapore/1/57. The results of the HAI test with antisera to purified HA indicate that virus A/Leningrad/549/80 contains HA similar to that of viruses A(H2N2) isolated in 1957, but not in 1964. The HAI test with the sera of polecats having the infection permits the differentiation of viruses A/Leningrad/80 from epidemic viruses A(H2N2) isolated in 1957-1965, including reference virus A/Singapore/1/57. In relation to the latter, the isolates of 1980 are older antigenic mutants. The isolates of 1980 are distinguished from virus A(H2N2), isolated in 1975 from the system of persisting influenza infection in a tissue culture, by mutation in NS-gene and the properties of RNA-polymerase. The authenticity of the isolation of viruses A(H2N2) in Leningrad in 1980 has been proved.
PubMed: 6240876
Affiliations:
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Le document en format XML
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Poliakov</name></author><author><name sortKey="Litvinova, O M" sort="Litvinova, O M" uniqKey="Litvinova O" first="O M" last="Litvinova">O M Litvinova</name></author><author><name sortKey="Bannikov, A I" sort="Bannikov, A I" uniqKey="Bannikov A" first="A I" last="Bannikov">A I Bannikov</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1984">1984</date><idno type="RBID">pubmed:6240876</idno><idno type="pmid">6240876</idno><idno type="wicri:Area/PubMed/Corpus">000514</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000514</idno><idno type="wicri:Area/PubMed/Curation">000514</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000514</idno><idno type="wicri:Area/PubMed/Checkpoint">000454</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000454</idno><idno type="wicri:Area/Ncbi/Merge">001187</idno><idno type="wicri:Area/Ncbi/Curation">001187</idno><idno type="wicri:Area/Ncbi/Checkpoint">001187</idno><idno type="wicri:doubleKey">0372-9311:1984:Golubev D:antigenic:anachronism:of</idno><idno type="wicri:Area/Main/Merge">002606</idno><idno type="wicri:Area/Main/Curation">002483</idno><idno type="wicri:Area/Main/Exploration">002483</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Antigenic anachronism of influenza viruses A(H2N2) in Leningrad in 1980. 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Poliakov</name></author><author><name sortKey="Litvinova, O M" sort="Litvinova, O M" uniqKey="Litvinova O" first="O M" last="Litvinova">O M Litvinova</name></author><author><name sortKey="Bannikov, A I" sort="Bannikov, A I" uniqKey="Bannikov A" first="A I" last="Bannikov">A I Bannikov</name></author></analytic><series><title level="j">Zhurnal mikrobiologii, epidemiologii, i immunobiologii</title><idno type="ISSN">0372-9311</idno><imprint><date when="1984" type="published">1984</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antigens, Viral (analysis)</term><term>Cross Reactions</term><term>DNA-Directed RNA Polymerases (analysis)</term><term>Hemagglutination Inhibition Tests</term><term>Humans</term><term>Influenza A Virus, H2N2 Subtype</term><term>Influenza A virus (enzymology)</term><term>Influenza A virus (immunology)</term><term>Influenza A virus (isolation & purification)</term><term>Neuraminidase (antagonists & inhibitors)</term><term>Nucleic Acid Hybridization</term><term>Peptides (analysis)</term><term>RNA, Viral (genetics)</term><term>Russia</term><term>Viral Proteins (analysis)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ARN viral (génétique)</term><term>Animaux</term><term>Antigènes viraux (analyse)</term><term>DNA-directed RNA polymerases (analyse)</term><term>Humains</term><term>Hybridation d'acides nucléiques</term><term>Peptides (analyse)</term><term>Protéines virales (analyse)</term><term>Russie</term><term>Réactions croisées</term><term>Sialidase (antagonistes et inhibiteurs)</term><term>Sous-type H2N2 du virus de la grippe A</term><term>Tests d'inhibition de l'hémagglutination</term><term>Virus de la grippe A (enzymologie)</term><term>Virus de la grippe A (immunologie)</term><term>Virus de la grippe A (isolement et purification)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Antigens, Viral</term><term>DNA-Directed RNA Polymerases</term><term>Peptides</term><term>Viral Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="antagonists & inhibitors" xml:lang="en"><term>Neuraminidase</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Russia</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Antigènes viraux</term><term>DNA-directed RNA polymerases</term><term>Peptides</term><term>Protéines virales</term></keywords><keywords scheme="MESH" qualifier="antagonistes et inhibiteurs" xml:lang="fr"><term>Sialidase</term></keywords><keywords scheme="MESH" qualifier="enzymologie" xml:lang="fr"><term>Virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="enzymology" xml:lang="en"><term>Influenza A virus</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>RNA, Viral</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>ARN viral</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Influenza A virus</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Influenza A virus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Virus de la grippe A</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Cross Reactions</term><term>Hemagglutination Inhibition Tests</term><term>Humans</term><term>Influenza A Virus, H2N2 Subtype</term><term>Nucleic Acid Hybridization</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Humains</term><term>Hybridation d'acides nucléiques</term><term>Russie</term><term>Réactions croisées</term><term>Sous-type H2N2 du virus de la grippe A</term><term>Tests d'inhibition de l'hémagglutination</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">As indicated by the results of the hemagglutination inhibition (HAI) test, influenza viruses A/Leningrad/80 contain hemagglutinin (HA), similar to that of virus A/Singapore/1/57 (H2N2). Neuraminidase contained in viruses A/Leningrad/80 belongs to serological subtype N2 and is similar to that of virus A/Singapore/1/57 (H2N2). No differences in the polypeptide composition of the virus-induced proteins of viruses A/Leningrad/527/80, A/Leningrad/549/80, A/Leningrad/553/80 and virus A/Singapore/1/57 used as reference have been detected in the study of their electrophoretic mobility in polyacrylamide gel, as well as the mobility of duplexes obtained by the hybridization of the virion and complement RNA of viruses A/Leningrad/553/80 and A/Singapore/1/57. The results of the HAI test with antisera to purified HA indicate that virus A/Leningrad/549/80 contains HA similar to that of viruses A(H2N2) isolated in 1957, but not in 1964. The HAI test with the sera of polecats having the infection permits the differentiation of viruses A/Leningrad/80 from epidemic viruses A(H2N2) isolated in 1957-1965, including reference virus A/Singapore/1/57. In relation to the latter, the isolates of 1980 are older antigenic mutants. The isolates of 1980 are distinguished from virus A(H2N2), isolated in 1975 from the system of persisting influenza infection in a tissue culture, by mutation in NS-gene and the properties of RNA-polymerase. The authenticity of the isolation of viruses A(H2N2) in Leningrad in 1980 has been proved.</div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Bannikov, A I" sort="Bannikov, A I" uniqKey="Bannikov A" first="A I" last="Bannikov">A I Bannikov</name><name sortKey="Galitarov, S S" sort="Galitarov, S S" uniqKey="Galitarov S" first="S S" last="Galitarov">S S Galitarov</name><name sortKey="Golubev, D B" sort="Golubev, D B" uniqKey="Golubev D" first="D B" last="Golubev">D B Golubev</name><name sortKey="Litvinova, O M" sort="Litvinova, O M" uniqKey="Litvinova O" first="O M" last="Litvinova">O M Litvinova</name><name sortKey="Poliakov, Iu M" sort="Poliakov, Iu M" uniqKey="Poliakov I" first="Iu M" last="Poliakov">Iu M. Poliakov</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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